Endocrine Abstracts

Background: Obesity exacerbates many aspects of the PCOS phenotype, especially cardiovascular risk factors, infertility. The objective of the study was to determine the effects of overweight and obesity on the metabolic features of PCOS.Material and methods: 116 PCOS women (according to Rotterdam criteria, mean age 27.16±3.87 years) were investigated in Vilnius city (Lithuania) in 2009–2011. Height, body mass and waist circumference were measur...

Background: The objective of the study was to compare distributions of subcutaneous adipose tissue and metabolic parameters in lean women with PCOS and lean healthy women.Materials and methods: PCOS women (according to Rotterdam criteria, mean age 26.54±3.65 years) and 70 healthy control women (mean age 27.84±3.63 years) were investigated in Vilnius city (Lithuania) in 2009–2011. A skinfold caliper device was used to measure skinfolds thic...

The study aimed to investigate diet patterns and its association with metabolic features in patients with PCOS.Material and methods: 116 women with PCOS (according to Rotterdam criteria) were investigated in Vilnius city (Lithuania) in 2009–2011. Information about nutrition habits was collected utilizing qualitative food frequency questionnaire. Participants were tested for total testosterone, sex hormone-binding globulin, fasting glucose, insulin a...

The incidence of thyroid cancer (TC) is increasing over time. Follow up and adequate treatment of patients with TC is important in everyday routine practice. The aim of the study was to evaluate peculiarities of clinical and pathologic characteristics of patients with TC, and their management after surgery.Material and methods: We conducted retrospective review of medical records of 116 patients with TC after thyroid surgery followed up in Vilnius Antaka...

The objective was to assess rate of impaired glucose regulation and progression to diabetes in adults using routinely collected health-care data.Material and methods: We conducted an audit on results of 75-g standardized oral glucose tolerance tests (OGTT) performed at Vilnius Antakalnio Outpatient Clinic from 3rd Jan 2011 to 15th Dec 2014 and analysed data of adult patients. We excluded from analysis results of 358 patients who didn’t perform 2-h p...

Mood disturbances accompanying the symptoms and hormonal abnormalities are important, but underestimated, in polycystic ovary syndrome (PCOS). Our objective was to assess psychological features in women with and without PCOS.Materials and methods: We investigated 116 PCOS women (according to the Rotterdam criteria) and 81 healthy control women in Vilnius city (Lithuania) in 2009–2011. Levels of anxiety and depression were measured using the Hospital...

IntroductionInternet searches mirror – to a degree – real-life behaviors and are influenced by chronic situations or abrupt events. From 2019 onwards the advent of the COVID-19 pandemic has changed profoundly daily habits, particularly during periods of protracted lockdown and following stay-at-home orders.AimIn this study we aimed to assess Google Trends internet searches for diet and obesity over ...

Objective: To evaluate cancer risk among people with type 2 diabetes mellitus (T2DM) in Lithuania.Methods: A retrospective cohort design was used. The cohort was established by identifying all patients with the first diagnosis of T2DM in the National Health Insurance Fund database during 2000–2012. Cancer cases were identified by record linkage with the Lithuanian Cancer Registry. Standardized incidence ratios (SIRs) were calculated.<p class="ab...

: Two-way interactions between thyroid and kidney functions are known. Chronic kidney disease (CKD) is accompanied by changes in synthesis, secretion, metabolism, and elimination of thyroid hormones, increased risk of hypothyroidism, rarely subclinical hyperthyroidism, whereas thyroid dysfunction affects physiology of the kidney, renal blood flow, glomerular filtration rate (GFR), tubular function, metabolism of water and electrolytes, and kidney structure. The aim of the stud...

Oral glucose tolerance test (OGTT) is the main tool in population based screening for type 2 diabetes mellitus. Sometimes OGTT results are showing asymptomatic lowering of post-load blood glucose. Post-load plasma glucose (2hPG) level 3.9 mmol/l (70 mg/dl) and lower shows biochemical hypoglycaemia. Biochemical hypoglycaemia might be observed among individuals with abnormal glucose tolerance and in healthy population. The objective of the investigation was to assess a prevalenc...